Item Type | Name |
Concept
|
Age Factors
|
Concept
|
Administration, Inhalation
|
Concept
|
Azaguanine
|
Concept
|
Aminoimidazole Carboxamide
|
Concept
|
Algorithms
|
Concept
|
Administration, Oral
|
Concept
|
Cardiac Pacing, Artificial
|
Concept
|
Anti-Inflammatory Agents, Non-Steroidal
|
Concept
|
Antineoplastic Combined Chemotherapy Protocols
|
Concept
|
Chromatography, DEAE-Cellulose
|
Concept
|
Analysis of Variance
|
Concept
|
Antibodies, Monoclonal
|
Concept
|
Arthritis, Rheumatoid
|
Concept
|
Arylsulfatases
|
Concept
|
B-Lymphocytes
|
Concept
|
Base Sequence
|
Concept
|
Benzamides
|
Concept
|
Benzoates
|
Concept
|
DNA Polymerase II
|
Concept
|
Azacitidine
|
Concept
|
Autoantibodies
|
Concept
|
Bacillus subtilis
|
Concept
|
Birth Weight
|
Concept
|
Echoencephalography
|
Concept
|
Blast Crisis
|
Concept
|
Blood Viscosity
|
Concept
|
Biomechanical Phenomena
|
Concept
|
Biopsy
|
Concept
|
Bone Marrow
|
Concept
|
Emergency Treatment
|
Concept
|
Cell Division
|
Concept
|
Evaluation Studies as Topic
|
Concept
|
Cellulose
|
Concept
|
Carbon Radioisotopes
|
Concept
|
Catalase
|
Concept
|
Choroid
|
Concept
|
Chicago
|
Concept
|
Child Development
|
Concept
|
Chromosome Mapping
|
Concept
|
Clinical Competence
|
Concept
|
Glucosephosphate Dehydrogenase
|
Concept
|
Gout
|
Concept
|
Creatinine
|
Concept
|
Cricetulus
|
Concept
|
Chondrocalcinosis
|
Concept
|
Chromatography, Ion Exchange
|
Concept
|
Coronary Artery Disease
|
Concept
|
Homozygote
|
Concept
|
Imidazoles
|
Concept
|
Dexamethasone
|
Concept
|
Diphosphoglyceric Acids
|
Concept
|
Injections, Intra-Arterial
|
Concept
|
Equipment Design
|
Concept
|
Decision Support Techniques
|
Concept
|
Cause of Death
|
Concept
|
DNA Mutational Analysis
|
Concept
|
Dogs
|
Concept
|
Dosage Compensation, Genetic
|
Concept
|
Echocardiography
|
Concept
|
Gene Frequency
|
Concept
|
Glucocorticoids
|
Concept
|
Gout Suppressants
|
Concept
|
Health Surveys
|
Concept
|
Hemoglobin, Sickle
|
Concept
|
Lesch-Nyhan Syndrome
|
Concept
|
Enzyme Inhibitors
|
Concept
|
Chromatography, High Pressure Liquid
|
Concept
|
Clinical Protocols
|
Concept
|
Exons
|
Concept
|
Amifostine
|
Concept
|
Etoposide
|
Concept
|
Cytarabine
|
Concept
|
Deafness
|
Concept
|
Double-Blind Method
|
Concept
|
Drug Administration Routes
|
Concept
|
Drug Therapy, Combination
|
Concept
|
Faculty, Medical
|
Concept
|
Fibroblasts
|
Concept
|
Mediastinal Emphysema
|
Concept
|
Electrocardiography
|
Concept
|
Electrophoresis
|
Concept
|
Enzyme Activation
|
Concept
|
Fluorescein Angiography
|
Concept
|
Gene Expression Regulation
|
Concept
|
Decision Making
|
Concept
|
Genes, Dominant
|
Concept
|
Gluconates
|
Concept
|
Glucosephosphate Dehydrogenase Deficiency
|
Concept
|
Genes
|
Concept
|
Glomerular Filtration Rate
|
Concept
|
Feasibility Studies
|
Concept
|
Nitrogen
|
Concept
|
Kidney Diseases
|
Concept
|
Graft Rejection
|
Concept
|
Disability Evaluation
|
Concept
|
Nucleic Acid Hybridization
|
Concept
|
Obesity
|
Concept
|
Hematologic Diseases
|
Concept
|
Hematopoietic Stem Cells
|
Concept
|
Education, Nursing, Baccalaureate
|
Concept
|
DNA Topoisomerases, Type I
|
Concept
|
Drug Combinations
|
Concept
|
Hydrogen-Ion Concentration
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
Concept
|
Clinical Enzyme Tests
|
Concept
|
Equipment Safety
|
Concept
|
Escherichia coli
|
Concept
|
Hypergammaglobulinemia
|
Concept
|
Feedback
|
Concept
|
Infusions, Intravenous
|
Concept
|
Gadolinium
|
Concept
|
Immunodiffusion
|
Concept
|
Isoenzymes
|
Concept
|
Leukocytes, Mononuclear
|
Concept
|
Lung Compliance
|
Concept
|
Managed Care Programs
|
Concept
|
Isoelectric Point
|
Concept
|
Medical Records
|
Concept
|
Pilot Projects
|
Concept
|
Liver Function Tests
|
Concept
|
Nasopharyngitis
|
Concept
|
Extremities
|
Concept
|
Illinois
|
Concept
|
Molecular Biology
|
Concept
|
Morbidity
|
Concept
|
Mutation
|
Concept
|
Myocardial Contraction
|
Concept
|
Cricetinae
|
Concept
|
Hot Temperature
|
Concept
|
Patient Education as Topic
|
Concept
|
Niridazole
|
Concept
|
Phenols
|
Concept
|
Nicotinic Acids
|
Concept
|
Pacemaker, Artificial
|
Concept
|
Pedigree
|
Concept
|
Patient Acceptance of Health Care
|
Concept
|
Sjogren's Syndrome
|
Concept
|
Skin Tests
|
Concept
|
Methylene Blue
|
Concept
|
Microscopy, Electron
|
Concept
|
Oxygen
|
Concept
|
Pancytopenia
|
Concept
|
Feeding Behavior
|
Concept
|
Probability
|
Concept
|
Thrombocytopenia
|
Concept
|
Piperazines
|
Concept
|
Plasmids
|
Concept
|
Glutamine
|
Concept
|
Hypoxanthines
|
Concept
|
Immunoglobulin G
|
Concept
|
Immunoelectrophoresis
|
Concept
|
Guanine
|
Concept
|
Health Status Indicators
|
Concept
|
Rabbits
|
Concept
|
Risk Factors
|
Concept
|
Radiography
|
Concept
|
ROC Curve
|
Concept
|
Cohort Studies
|
Concept
|
Sexual Dysfunction, Physiological
|
Concept
|
Respiratory Function Tests
|
Concept
|
Sex Chromosomes
|
Concept
|
Risk
|
Concept
|
Sensitivity and Specificity
|
Concept
|
Humans
|
Concept
|
Human Development
|
Concept
|
Tomography, Emission-Computed, Single-Photon
|
Concept
|
Body Mass Index
|
Concept
|
Incidence
|
Concept
|
Cluster Analysis
|
Concept
|
Linear Models
|
Concept
|
Stress, Mechanical
|
Concept
|
Tomography, X-Ray Computed
|
Concept
|
Tritium
|
Concept
|
Intensive Care Units, Neonatal
|
Concept
|
Ultrasonography
|
Concept
|
Stroke Volume
|
Concept
|
Tumor Necrosis Factor-alpha
|
Concept
|
Practice Guidelines as Topic
|
Concept
|
Genetic Variation
|
Concept
|
Ultraviolet Rays
|
Concept
|
Echocardiography, Doppler
|
Concept
|
Leukemia, Myeloid
|
Concept
|
Lipidoses
|
Concept
|
Proportional Hazards Models
|
Concept
|
Randomized Controlled Trials as Topic
|
Concept
|
Risk Assessment
|
Concept
|
Drug Resistance, Neoplasm
|
Concept
|
Caspases
|
Concept
|
Ventricular Function, Left
|
Concept
|
Arthritis, Gouty
|
Concept
|
Prevalence
|
Concept
|
Observer Variation
|
Concept
|
Pentostatin
|
Concept
|
Lupus Erythematosus, Systemic
|
Concept
|
Milk
|
Concept
|
Mortality
|
Concept
|
Multiple Myeloma
|
Concept
|
Leukemia, Myeloid, Acute
|
Concept
|
Chi-Square Distribution
|
Concept
|
Comorbidity
|
Concept
|
Clinical Trials, Phase II as Topic
|
Concept
|
Neuromyelitis Optica
|
Concept
|
Case-Control Studies
|
Concept
|
Sequence Analysis, DNA
|
Concept
|
Treatment Outcome
|
Concept
|
New York
|
Concept
|
Scleroderma, Diffuse
|
Concept
|
Point Mutation
|
Concept
|
Crystallography, X-Ray
|
Concept
|
Gene Expression Regulation, Developmental
|
Concept
|
DNA, Complementary
|
Concept
|
Antigens, CD20
|
Concept
|
Multiple Sclerosis, Relapsing-Remitting
|
Concept
|
Metabolic Syndrome
|
Concept
|
Cross-Over Studies
|
Concept
|
Orotic Acid
|
Concept
|
Oxypurinol
|
Concept
|
Multiple Sclerosis, Chronic Progressive
|
Concept
|
Cladribine
|
Concept
|
Self Report
|
Concept
|
Fatal Outcome
|
Concept
|
Early Diagnosis
|
Concept
|
Consensus
|
Concept
|
Proteomics
|
Concept
|
Renal Insufficiency, Chronic
|
Concept
|
Area Under Curve
|
Concept
|
Patient Participation
|
Concept
|
Gene Expression Profiling
|
Concept
|
Physicians, Family
|
Concept
|
Physical Examination
|
Concept
|
Physicians
|
Concept
|
Polyethylene Glycols
|
Concept
|
Pneumonia
|
Concept
|
Precipitin Tests
|
Concept
|
Mice
|
Concept
|
Purine-Pyrimidine Metabolism, Inborn Errors
|
Concept
|
Pyrazoles
|
Concept
|
Pyrimidines
|
Concept
|
Pyrimidine Nucleotides
|
Concept
|
Diphosphates
|
Concept
|
Surveys and Questionnaires
|
Concept
|
Radioimmunoassay
|
Concept
|
Severity of Illness Index
|
Concept
|
Respiratory Distress Syndrome, Newborn
|
Concept
|
Steryl-Sulfatase
|
Concept
|
Rats
|
Concept
|
Chemoradiotherapy
|
Concept
|
Triazoles
|
Concept
|
Lost to Follow-Up
|
Concept
|
Antibodies, Monoclonal, Humanized
|
Concept
|
Trypsin
|
Concept
|
Uridine
|
Concept
|
Sex Factors
|
Concept
|
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
|
Concept
|
Serine Proteinase Inhibitors
|
Concept
|
Multivariate Analysis
|
Concept
|
Logistic Models
|
Concept
|
Heart Transplantation
|
Concept
|
Thiazoles
|
Concept
|
Cyclosporine
|
Concept
|
Electronic Health Records
|
Concept
|
Sialic Acid Binding Ig-like Lectin 2
|
Concept
|
Uricosuric Agents
|
Concept
|
6-Aminonicotinamide
|
Concept
|
Blotting, Southern
|
Concept
|
Blotting, Northern
|
Concept
|
Reproducibility of Results
|
Concept
|
Treatment Failure
|
Concept
|
Lung Diseases, Interstitial
|
Concept
|
Gene Expression Regulation, Enzymologic
|
Concept
|
Survival Rate
|
Concept
|
Confidence Intervals
|
Concept
|
Odds Ratio
|
Concept
|
Polymerase Chain Reaction
|
Concept
|
Granulocyte Colony-Stimulating Factor
|
Concept
|
Lymphoma, Large B-Cell, Diffuse
|
Concept
|
Coronary Angiography
|
Concept
|
Clinical Trials, Phase III as Topic
|
Concept
|
Imaging, Three-Dimensional
|
Concept
|
Xenograft Model Antitumor Assays
|
Concept
|
Echocardiography, Stress
|
Concept
|
HSP90 Heat-Shock Proteins
|
Concept
|
Hematologic Neoplasms
|
Concept
|
Histone Deacetylase Inhibitors
|
Concept
|
Transcriptome
|
Concept
|
B-Cell Activating Factor
|
Concept
|
Consolidation Chemotherapy
|
Concept
|
Antibodies, Monoclonal, Murine-Derived
|
Concept
|
Adolescent Development
|
Concept
|
Renal Insufficiency
|
Concept
|
Intention to Treat Analysis
|
Concept
|
Airway Resistance
|
Concept
|
Antibodies
|
Concept
|
Antibodies, Antinuclear
|
Concept
|
Bronchopulmonary Dysplasia
|
Concept
|
Cell Survival
|
Concept
|
Clinical Trials as Topic
|
Concept
|
Cloning, Molecular
|
Concept
|
Delayed-Action Preparations
|
Concept
|
Diabetes Mellitus
|
Concept
|
Disease Models, Animal
|
Concept
|
Drug Administration Schedule
|
Concept
|
Erythrocytes
|
Concept
|
Family Practice
|
Concept
|
Follow-Up Studies
|
Concept
|
Form Perception
|
Concept
|
Gestational Age
|
Concept
|
Glucose
|
Concept
|
Guanosine Diphosphate
|
Concept
|
Heterozygote
|
Concept
|
India
|
Concept
|
Injections, Subcutaneous
|
Concept
|
Kinetics
|
Concept
|
Genetic Linkage
|
Concept
|
Lymphocytes
|
Concept
|
Magnetic Resonance Imaging
|
Concept
|
Metabolism, Inborn Errors
|
Concept
|
Monitoring, Physiologic
|
Concept
|
Monocytes
|
Concept
|
Pain Measurement
|
Concept
|
Patient Compliance
|
Concept
|
Patient Dropouts
|
Concept
|
Phosphates
|
Concept
|
Predictive Value of Tests
|
Concept
|
Prospective Studies
|
Concept
|
Respiration, Artificial
|
Concept
|
Retrospective Studies
|
Concept
|
X Chromosome
|
Concept
|
Restriction Mapping
|
Concept
|
Discriminant Analysis
|
Concept
|
Mice, SCID
|
Concept
|
Mice, Inbred NOD
|
Concept
|
Age of Onset
|
Concept
|
Disease-Free Survival
|
Concept
|
Polymorphism, Single-Stranded Conformational
|
Concept
|
Computational Biology
|
Concept
|
Genetic Predisposition to Disease
|
Concept
|
Polymorphism, Single Nucleotide
|
Concept
|
Maintenance Chemotherapy
|
Concept
|
Early Medical Intervention
|
Academic Article
|
Human phosphoribosylpyrophosphate synthetase (PRS) 2: an independent active, X chromosome-linked PRS isoform.
|
Academic Article
|
Structural analysis of polymers of sickle cell hemoglobin. III. Fibers within fascicles.
|
Academic Article
|
Clinical aspects of monosodium urate monohydrate crystal deposition disease (gout).
|
Academic Article
|
Point mutations in PRPS1, the gene encoding the PRPP synthetase (PRS) 1 isoform, underlie X-linked PRS superactivity associated with purine nucleotide inhibitor-resistance.
|
Academic Article
|
Overexpression of the normal phosphoribosylpyrophosphate synthetase 1 isoform underlies catalytic superactivity of human phosphoribosylpyrophosphate synthetase.
|
Academic Article
|
Immediate changes in lung compliance following natural surfactant administration in premature infants with respiratory distress syndrome: a controlled trial.
|
Academic Article
|
Outcome measures for acute and chronic gout.
|
Academic Article
|
Febuxostat compared with allopurinol in patients with hyperuricemia and gout.
|
Academic Article
|
Phase I study of cladribine, cytarabine (Ara-C), granulocyte colony stimulating factor (G-CSF) (CLAG Regimen) and simultaneous escalating doses of imatinib mesylate (Gleevec) in relapsed/refractory AML.
|
Academic Article
|
Tophaceous gout: quantitative evaluation by direct physical measurement.
|
Academic Article
|
Compliance with allopurinol therapy among managed care enrollees with gout: a retrospective analysis of administrative claims.
|
Academic Article
|
Tophus measurement as an outcome measure for clinical trials of chronic gout: progress and research priorities.
|
Academic Article
|
Serum urate in chronic gout--will it be the first validated soluble biomarker in rheumatology?
|
Academic Article
|
Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: two randomized controlled trials.
|
Academic Article
|
Clinical efficacy and safety of successful longterm urate lowering with febuxostat or allopurinol in subjects with gout.
|
Academic Article
|
Hyperuricemia and associated diseases.
|
Academic Article
|
Quality of life and disability in patients with treatment-failure gout.
|
Academic Article
|
Trade-off in object versus spatial visualization abilities: restriction in the development of visual-processing resources.
|
Academic Article
|
Patient-reported outcomes in chronic gout: a report from OMERACT 10.
|
Academic Article
|
Treating hyperuricemia of gout: safety and efficacy of febuxostat and allopurinol in older versus younger subjects.
|
Academic Article
|
Regulation of purine synthesis de novo in human fibroblasts by purine nucleotides and phosphoribosylpyrophosphate.
|
Academic Article
|
Inherited superactivity of phosphoribosylpyrophosphate synthetase: association of uric acid overproduction and sensorineural deafness.
|
Academic Article
|
Tacrolimus and steroids versus ciclosporin microemulsion, steroids, and azathioprine in children undergoing liver transplantation: randomised European multicentre trial.
|
Academic Article
|
Outcome evaluations in gout.
|
Academic Article
|
The SPINK1 N34S variant is associated with acute pancreatitis.
|
Academic Article
|
Bringing it all together: a novel approach to the development of response criteria for chronic gout clinical trials.
|
Academic Article
|
Infusion-related reactions with pegloticase, a recombinant uricase for the treatment of chronic gout refractory to conventional therapy.
|
Academic Article
|
The hematopoietic cell transplantation specific comorbidity index and survival after extracorporeal photopheresis, pentostatin, and reduced dose total body irradiation conditioning prior to allogeneic stem cell transplantation.
|
Academic Article
|
A phase I study of decitabine and rapamycin in relapsed/refractory AML.
|
Academic Article
|
Long-term management of gout: nonpharmacologic and pharmacologic therapies.
|
Academic Article
|
Rapid method for detection of mutations in the nucleophosmin gene in acute myeloid leukemia.
|
Academic Article
|
Summary of the 2015 Purine and Pyrimidine Society/Purine Metabolic Patients Association H. Anne Simmonds Memorial Lecture.
|
Academic Article
|
Patterns and Timing of Failure for Diffuse Large B-Cell Lymphoma After Initial Therapy in a Cohort Who Underwent Autologous Bone Marrow Transplantation for Relapse.
|
Academic Article
|
Purine metabolism in normal and thioguanine-resistant neuroblastoma.
|
Academic Article
|
Mitogenic enhancement of purine base phosphoribosylation in Swiss mouse 3T3 cells.
|
Academic Article
|
Ventilatory management casebook. Successful treatment of pulmonary interstitial emphysema with high-frequency oscillation after unsuccessful high-frequency jet ventilation.
|
Academic Article
|
Identification of distinct PRS1 mutations in two patients with X-linked phosphoribosylpyrophosphate synthetase superactivity.
|
Academic Article
|
Mechanisms of accelerated purine nucleotide synthesis in human fibroblasts with superactive phosphoribosylpyrophosphate synthetases.
|
Academic Article
|
Increased PP-ribose-P synthetase activity: a genetic abnormality leading to excessive purine production and gout.
|
Academic Article
|
Human erythrocyte phosphoribosylpyrophosphate synthetase. Dependence of activity on state of subunit association.
|
Academic Article
|
Synthesis of phosphoribosylpyrophosphate in mammalian cells.
|
Academic Article
|
Regional localization of the gene for human phosphoribosylpyrophosphate synthetase on the X chromosome.
|
Academic Article
|
Superactive phosphoribosylpyrophosphate synthetase with altered regulatory and catalytic properties.
|
Academic Article
|
PRPP synthetase superactivity in lymphoblast lines.
|
Academic Article
|
Inherited phosphoribosylpyrophosphate synthetase superactivity due to aberrant inhibitor and activator responsiveness.
|
Academic Article
|
Human X-linked phosphoribosylpyrophosphate synthetase superactivity is associated with distinct point mutations in the PRPS1 gene.
|
Academic Article
|
Human erythrocyte phosphoribosylpyrophosphate synthetase. Subunit analysis and states of subunit association.
|
Academic Article
|
Determinants of 5-phosphoribosyl-1-pyrophosphate (PRPP) synthesis in human fibroblasts.
|
Academic Article
|
Determination of the activity of recombinant human phosphoribosylpyrophosphate synthetase isoform 1 by a non-isotopic, one-step method.
|
Academic Article
|
Sex on the internet: furthering our understanding of men with online sexual problems.
|
Academic Article
|
Real-time pulmonary graphic monitoring.
|
Academic Article
|
Human phosphoribosylpyrophosphate (PRPP) synthetase requirements for subunit aggregation.
|
Academic Article
|
Phosphoribosylpyrophosphate synthetase superactivity. A study of five patients with catalytic defects in the enzyme.
|
Academic Article
|
Human phosphoribosylpyrophosphate synthetase. Comparison of purified normal and mutant enzymes.
|
Academic Article
|
Efficacy and safety of febuxostat extended release and immediate release in patients with gout and moderate renal impairment: phase II placebo-controlled study.
|
Academic Article
|
Diminished affinity for purine substrates as a basis for gout with mild deficiency of hypoxanthine-guanine phosphoribosyltransferase.
|
Academic Article
|
Effects of inosine on purine synthesis in normal and HGPRT-deficient human fibroblasts.
|
Academic Article
|
Inflammation: a possible mechanism for a causative role of hyperuricemia/gout in cardiovascular disease.
|
Academic Article
|
Superfluorescence from lead halide perovskite quantum dot superlattices.
|
Academic Article
|
Long Exciton Dephasing Time and Coherent Phonon Coupling in CsPbBr2Cl Perovskite Nanocrystals.
|
Academic Article
|
Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout.
|
Academic Article
|
Patterns of phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in fibroblasts from patients with gout and purine overproduction.
|
Academic Article
|
Efficacy and Safety of Febuxostat Extended and Immediate Release in Patients With Gout and Renal Impairment: A Phase III Placebo-Controlled Study.
|
Academic Article
|
Polymer and Colloid Highlights.
|
Academic Article
|
Electronic Health Record Mortality Prediction Model for Targeted Palliative Care Among Hospitalized Medical Patients: a Pilot Quasi-experimental Study.
|
Academic Article
|
A phase II clinical trial of lenalidomide intensification in patients with serologic/asymptomatic progression of multiple myeloma while on lenalidomide maintenance: a tri-state transplant consortium study.
|
Academic Article
|
Speckle Tracking Echocardiography and All-Cause and Cardiovascular Mortality Risk in Chronic Kidney Disease Patients.
|
Academic Article
|
Trion Emission Dominates the Low-Temperature Photoluminescence of CdSe Nanoplatelets.
|
Academic Article
|
Unraveling the Origin of the Long Fluorescence Decay Component of Cesium Lead Halide Perovskite Nanocrystals.
|
Academic Article
|
Parkinson's Disease Medication Administration During a Care Transition: The Impact of Interprofessional Team Simulation on Student Competency, Comfort, and Knowledge.
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Academic Article
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Evaluation of the Relationship Between Serum Urate Levels, Clinical Manifestations of Gout, and Death From Cardiovascular Causes in Patients Receiving Febuxostat or Allopurinol in an Outcomes Trial.
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Academic Article
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Robust Tipless Positioning Device for Near-Field Investigations: Press and Roll Scan (PROscan).
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Concept
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Imatinib Mesylate
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Concept
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Etanercept
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Concept
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Rituximab
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Concept
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Infliximab
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Concept
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Febuxostat
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Concept
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Febrile Neutropenia
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Concept
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Factor Xa Inhibitors
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Concept
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Multimodal Imaging
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Concept
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Non-Randomized Controlled Trials as Topic
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Concept
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Surgeons
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Grant
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REGULATION OF PURINE NUCLEOTIDE SYNTHESIS IN HUMANS
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Academic Article
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Changing patterns of otitis media in the Waikato region during the COVID-19 pandemic.
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